ROCHESTER — In a report, the National Transportation Safety Board finds a defect in the plane's cabin design was in part responsible for a deadly plane crash that took the lives of a prominent Rochester developer and his wife.

On Sept. 5, 2014, Larry and Jane Glazer died after their plane went down off the coast of Jamaica. After taking off in Rochester headed to Florida, the plane stopped communicating with air traffic control. When military planes responded, they found both Glazers unconscious in the plane — a result of hypoxia.

However, the plane appeared to be flying normally, and continued in the air until it ran out of fuel and crashed in the Caribbean Sea.

Now, a new NTSB report finds a cabin design flaw may be to blame for the crash.

For a probable cause, NTSB investigators write: "The design of the cabin pressurization system, which made it prone to unnecessary shutdown, combined with a checklist design that prioritized troubleshooting over ensuring that the pilot was sufficiently protected from hypoxia. This resulted in a loss of cabin pressure that rendered the pilot and passenger unconscious during cruise flight and eventually led to an in-flight loss of power due to fuel exhaustion over the open ocean."

As a developer, Larry Glazer — managing partner of Buckingham Properties LLC — bought up dozens of properties in Rochester, including landmark buildings belonging to the manufacturing giants Xerox Corp. and Bausch & Lomb. He converted abandoned factories into loft apartments and turned a shuttered hospital into offices. He also was involved in several Ontario County projects.

Jane Glazer was the founder of household-products catalog company QCI Direct.